abnormal colon morphology_Gt(ROSA)26Sor<tm1.1(CAG-PLS3,-GFP)Bwir>/Gt(ROSA)26Sor<+>,Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/0

http://metadb.riken.jp/0000495I129P2OlaHsd129S4SvJaeBALBcJC57BL6FVBNGtROSA26Sortm11CAGPLS3GFPBwirGtROSA26SorSmn1tm1HungSmn1tm1HungTgSMN22Hung0GtROSA26SorTgSMN22HungGtROSA26Sortm11CAGPLS3GFPBwirSmn1tm1Hung

abnormal colon morphology_Gt(ROSA)26Sor<tm1.1(CAG-PLS3,-GFP)Bwir>/Gt(ROSA)26Sor<+>,Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, Hung Li
  http://metadb.riken.jp/db/mgi_rdf/MGI:3514027
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• survival motor neuron 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109257

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1.1(CAG-PLS3,-GFP)Bwir>/Gt(ROSA)26Sor<+>,Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Tg(SMN2)2Hung|Gt(ROSA)26Sor<tm1.1(CAG-PLS3,-GFP)Bwir>|Smn1<tm1Hung>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal colon morphology
  http://purl.obolibrary.org/obo/MP_0000495

文献

http://purl.org/net/cito/citesAsAuthority

• Bastian. Ackermann, et.al., Plastin 3 ameliorates spinal muscular atrophy via delayed axon pruning and improves neuromuscular junction functionality., Human molecular genetics, 2013, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/23263861