abnormal small intestine morphology_Itgb1<tm1Efu>/Itgb1<tm1Efu>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0000496I129X1SvJC57BL6JSJLItgb1tm1EfuItgb1tm1EfuTgVil1cre997Gum0Itgb1tm1EfuTgVil1cre997Gum

abnormal small intestine morphology_Itgb1<tm1Efu>/Itgb1<tm1Efu>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957
• integrin beta 1 (fibronectin receptor beta)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96610

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itgb1<tm1Efu>/Itgb1<tm1Efu>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itgb1<tm1Efu>|Tg(Vil1-cre)997Gum

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal small intestine morphology
  http://purl.obolibrary.org/obo/MP_0000496

文献

http://purl.org/net/cito/citesAsAuthority

• Robert G. Jones, et.al., Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality., The Journal of cell biology, 2006, 175
  http://rdf.ncbi.nlm.nih.gov/pubmed/17088430