abnormal forelimb morphology_Gt(ROSA)26Sor<tm1(Dkk1)Flng>/Gt(ROSA)26Sor<+>,Rac1<tm1Djk>/Rac1<+>,Tg(Msx2-cre)5Rem/0

http://metadb.riken.jp/0000550I129S4SvJae129X1SvJGtROSA26Sortm1Dkk1FlngGtROSA26SorRac1tm1DjkRac1TgMsx2cre5Rem0Rac1tm1DjkGtROSA26SorRac1TgMsx2cre5RemGtROSA26Sortm1Dkk1Flng

abnormal forelimb morphology_Gt(ROSA)26Sor<tm1(Dkk1)Flng>/Gt(ROSA)26Sor<+>,Rac1<tm1Djk>/Rac1<+>,Tg(Msx2-cre)5Rem/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RAS-related C3 botulinum substrate 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97845
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 5, Robert E Maxson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2159108

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Dkk1)Flng>/Gt(ROSA)26Sor<+>,Rac1<tm1Djk>/Rac1<+>,Tg(Msx2-cre)5Rem/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rac1<tm1Djk>|Gt(ROSA)26Sor<+>|Rac1<+>|Tg(Msx2-cre)5Rem|Gt(ROSA)26Sor<tm1(Dkk1)Flng>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal forelimb morphology
  http://purl.obolibrary.org/obo/MP_0000550

文献

http://purl.org/net/cito/citesAsAuthority

• Ximei. Wu, et.al., Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling., Cell, 2008, 133
  http://rdf.ncbi.nlm.nih.gov/pubmed/18423204