synostosis_Lrp5<tm1Lex>/Lrp5<tm1Lex>,Lrp6<Gt(Ex187)Byg>/Lrp6<+>

http://metadb.riken.jp/0000566I129Sv129P2OlaHsdC57BL6JFVBNLrp5tm1LexLrp5tm1LexLrp6GtEx187BygLrp6Lrp5tm1LexLrp6Lrp6GtEx187Byg

synostosis_Lrp5<tm1Lex>/Lrp5<tm1Lex>,Lrp6<Gt(Ex187)Byg>/Lrp6<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor-related protein 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1298218
• low density lipoprotein receptor-related protein 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1278315

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lrp5<tm1Lex>/Lrp5<tm1Lex>,Lrp6<Gt(Ex187)Byg>/Lrp6<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lrp5<tm1Lex>|Lrp6<+>|Lrp6<Gt(Ex187)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• synostosis
  http://purl.obolibrary.org/obo/MP_0000566

文献

http://purl.org/net/cito/citesAsAuthority

• Sheri L. Holmen, et.al., Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2004, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/15537447