abnormal liver morphology_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(Alb1-cre)7Gsc/0

http://metadb.riken.jp/0000598I129C57BL6FVBNCol1a1tm1tetOFosWagCol1a1GtROSA26Sortm1rtTAEGFPNagyGtROSA26SorTgAlb1cre7Gsc0TgAlb1cre7GscGtROSA26Sortm1rtTAEGFPNagyGtROSA26SorCol1a1Col1a1tm1tetOFosWag

abnormal liver morphology_Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(Alb1-cre)7Gsc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 7, Gunther Schutz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177601
• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm1(tetO-Fos)Wag>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(Alb1-cre)7Gsc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb1-cre)7Gsc|Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>|Gt(ROSA)26Sor<+>|Col1a1<+>|Col1a1<tm1(tetO-Fos)Wag>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal liver morphology
  http://purl.obolibrary.org/obo/MP_0000598

文献

http://purl.org/net/cito/citesAsAuthority

• Sebastian C. Hasenfuss, et.al., Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers., Cell metabolism, 2014, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/24411941