abnormal liver morphology_Gt(ROSA)26Sor<tm3(HIF1A*)Kael>/Gt(ROSA)26Sor<tm4(HIF2A*)Kael>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0000598I129S6SvEvTacBALBcC57BL6DBAGtROSA26Sortm3HIF1AKaelGtROSA26Sortm4HIF2AKaelTgAlbcre21Mgn0GtROSA26Sortm4HIF2AKaelGtROSA26Sortm3HIF1AKaelTgAlbcre21Mgn

abnormal liver morphology_Gt(ROSA)26Sor<tm3(HIF1A*)Kael>/Gt(ROSA)26Sor<tm4(HIF2A*)Kael>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm3(HIF1A*)Kael>/Gt(ROSA)26Sor<tm4(HIF2A*)Kael>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm4(HIF2A*)Kael>|Gt(ROSA)26Sor<tm3(HIF1A*)Kael>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * BALB/c * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal liver morphology
  http://purl.obolibrary.org/obo/MP_0000598

文献

http://purl.org/net/cito/citesAsAuthority

• William Y. Kim, et.al., Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo., The EMBO journal, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16977322