amyloidosis_Tg(APP695)3Dbo/0,Tg(PSEN1dE9)S9Dbo/0

http://metadb.riken.jp/0000604I129S1Sv129X1SvJC3HHeJC57BL6JTgAPP6953Dbo0TgPSEN1dE9S9Dbo0TgAPP6953DboTgPSEN1dE9S9Dbo

amyloidosis_Tg(APP695)3Dbo/0,Tg(PSEN1dE9)S9Dbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion S9, David R Borchelt
  http://metadb.riken.jp/db/mgi_rdf/MGI:3618598
• transgene insertion 3, David R Borchelt
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448606

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(APP695)3Dbo/0,Tg(PSEN1dE9)S9Dbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APP695)3Dbo|Tg(PSEN1dE9)S9Dbo

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloidosis
  http://purl.obolibrary.org/obo/MP_0000604

文献

http://purl.org/net/cito/citesAsAuthority

• Fiona M. Laird, et.al., BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16354928