RDF of MGI data
表現型アノテーション
abnormal hepatocyte morphology_Krt8<tm1Rgo>/Krt8<tm1Rgo>
http://metadb.riken.jp/0000607I129S2SvPasC57BL6FVBNKrt8tm1RgoKrt8tm1RgoKrt8tm1Rgo
abnormal hepatocyte morphology_Krt8<tm1Rgo>/Krt8<tm1Rgo>(表現型アノテーション)
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abnormal hepatocyte morphology_Krt8<tm1Rgo>/Krt8<tm1Rgo>
表現型アノテーション
MGI marker
http://metadb.riken.jp/db/mgi_rdf/variant_of
keratin 8
http://metadb.riken.jp/db/mgi_rdf/MGI:96705
遺伝子型
http://metadb.riken.jp/db/mgi_rdf/allele_composition
Krt8<tm1Rgo>/Krt8<tm1Rgo>
アレルシンボル
http://metadb.riken.jp/db/mgi_rdf/allele_symbol
Krt8<tm1Rgo>
遺伝的背景
http://metadb.riken.jp/db/mgi_rdf/genetic_background
involves: 129S2/SvPas * C57BL/6 * FVB/N
MP annotation
http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype
abnormal hepatocyte morphology
http://purl.obolibrary.org/obo/MP_0000607
文献
http://purl.org/net/cito/citesAsAuthority
S. Gilbert, et.al., Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation., The Journal of cell biology, 2001, 154
http://rdf.ncbi.nlm.nih.gov/pubmed/11514590
Guo-Zhong. Tao, et.al., Keratin-8 null mice have different gallbladder and liver susceptibility to lithogenic diet-induced injury., Journal of cell science, 2003, 116
http://rdf.ncbi.nlm.nih.gov/pubmed/14576356
A. Loranger, et.al., Simple epithelium keratins are required for maintenance of hepatocyte integrity., The American journal of pathology, 1997, 151
http://rdf.ncbi.nlm.nih.gov/pubmed/9403718
D M. Toivola, et.al., Protein phosphatase inhibition in normal and keratin 8/18 assembly-incompetent mouse strains supports a functional role of keratin intermediate filaments in preserving hepatocyte integrity., Hepatology (Baltimore, Md.), 1998, 28
http://rdf.ncbi.nlm.nih.gov/pubmed/9657104
D M. Toivola, et.al., Disturbances in hepatic cell-cycle regulation in mice with assembly-deficient keratins 8/18., Hepatology (Baltimore, Md.), 2001, 34
http://rdf.ncbi.nlm.nih.gov/pubmed/11732007
C. Caulin, et.al., Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis., The Journal of cell biology, 2000, 149
http://rdf.ncbi.nlm.nih.gov/pubmed/10747083
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