abnormal hepatocyte morphology_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0000607I129X1SvJC57BL6DBAFoxm1tm1RhcFoxm1tm1RhcTgAlbcre21Mgn0Foxm1tm1RhcTgAlbcre21Mgn

abnormal hepatocyte morphology_Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box M1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1347487
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxm1<tm1Rhc>/Foxm1<tm1Rhc>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxm1<tm1Rhc>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal hepatocyte morphology
  http://purl.obolibrary.org/obo/MP_0000607

文献

http://purl.org/net/cito/citesAsAuthority

• Vladimir V. Kalinichenko, et.al., Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor., Genes & development, 2004, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/15082532
• Xinhe. Wang, et.al., The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/12482952