abnormal hepatocyte morphology_Tg(SERPINA1*E342K)#Slcw/0

http://metadb.riken.jp/0000607IC57BL6ICRTgSERPINA1E342KSlcw0TgSERPINA1E342KSlcw

abnormal hepatocyte morphology_Tg(SERPINA1*E342K)#Slcw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Savio L C Woo
  http://metadb.riken.jp/db/mgi_rdf/MGI:3847800

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(SERPINA1*E342K)#Slcw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(SERPINA1*E342K)#Slcw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal hepatocyte morphology
  http://purl.obolibrary.org/obo/MP_0000607

文献

http://purl.org/net/cito/citesAsAuthority

• Shuling. Guo, et.al., Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice., The Journal of clinical investigation, 2014, 124
  http://rdf.ncbi.nlm.nih.gov/pubmed/24355919
• J A. Carlson, et.al., Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice., The Journal of clinical investigation, 1989, 83
  http://rdf.ncbi.nlm.nih.gov/pubmed/2784798