abnormal liver physiology_Cyp8b1<tm1Rus>/Cyp8b1<tm1Rus>

http://metadb.riken.jp/0000609I129S7SvEvBrdC57BL6JCyp8b1tm1RusCyp8b1tm1RusCyp8b1tm1Rus

abnormal liver physiology_Cyp8b1<tm1Rus>/Cyp8b1<tm1Rus>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytochrome P450, family 8, subfamily b, polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338044

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cyp8b1<tm1Rus>/Cyp8b1<tm1Rus>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cyp8b1<tm1Rus>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal liver physiology
  http://purl.obolibrary.org/obo/MP_0000609

文献

http://purl.org/net/cito/citesAsAuthority

• Charlotte. Murphy, et.al., Cholic acid as key regulator of cholesterol synthesis, intestinal absorption and hepatic storage in mice., Biochimica et biophysica acta, 2005, 1735
  http://rdf.ncbi.nlm.nih.gov/pubmed/15994119
• Jia. Li-Hawkins, et.al., Cholic acid mediates negative feedback regulation of bile acid synthesis in mice., The Journal of clinical investigation, 2002, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/12393855