abnormal branching of the mammary ductal tree_Pik3ca<tm1Gne>/Pik3ca<+>,Tg(MMTV-cre)1Mam/0

http://metadb.riken.jp/0000662IC57BL6NFVBNPik3catm1GnePik3caTgMMTVcre1Mam0Pik3catm1GneTgMMTVcre1MamPik3ca

abnormal branching of the mammary ductal tree_Pik3ca<tm1Gne>/Pik3ca<+>,Tg(MMTV-cre)1Mam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1206581
• transgene insertion 1, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176162

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pik3ca<tm1Gne>/Pik3ca<+>,Tg(MMTV-cre)1Mam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pik3ca<tm1Gne>|Tg(MMTV-cre)1Mam|Pik3ca<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal branching of the mammary ductal tree
  http://purl.obolibrary.org/obo/MP_0000662

文献

http://purl.org/net/cito/citesAsAuthority

• W. Yuan, et.al., Conditional activation of Pik3ca(H1047R) in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations., Oncogene, 2013, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22370636