abnormal thyroid gland morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe/0,Tg(TPO-cre)1Shk/0

http://metadb.riken.jp/0000681I129S4SvJaeFVBNCrFVBNJPtentm1HwuPtentm1HwuTgCAGEGFPPAX8PPARG1Rkoe0TgTPOcre1Shk0Ptentm1HwuTgTPOcre1ShkTgCAGEGFPPAX8PPARG1Rkoe

abnormal thyroid gland morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe/0,Tg(TPO-cre)1Shk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 1, Ronald J Koenig
  http://metadb.riken.jp/db/mgi_rdf/MGI:5294344
• transgene insertion 1, Shioko Kimura
  http://metadb.riken.jp/db/mgi_rdf/MGI:3653643

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe/0,Tg(TPO-cre)1Shk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Tg(TPO-cre)1Shk|Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * FVB/NCr * FVB/NJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal thyroid gland morphology
  http://purl.obolibrary.org/obo/MP_0000681

文献

http://purl.org/net/cito/citesAsAuthority

• Melissa E. Dobson, et.al., Pioglitazone induces a proadipogenic antitumor response in mice with PAX8-PPARgamma fusion protein thyroid carcinoma., Endocrinology, 2011, 152
  http://rdf.ncbi.nlm.nih.gov/pubmed/21952241