abnormal spleen morphology_Pbx1<tm1Koss>/Pbx1<tm1Koss>,Pbx2<tm1Mlc>/Pbx2<+>,Nkx2-5<tm2(cre)Rph>/Nkx2-5<+>

http://metadb.riken.jp/0000689I129P2OlaHsd129SSv129S1SvPbx1tm1KossPbx1tm1KossPbx2tm1MlcPbx2Nkx25tm2creRphNkx25Nkx25Nkx25tm2creRphPbx2tm1MlcPbx1tm1KossPbx2

abnormal spleen morphology_Pbx1<tm1Koss>/Pbx1<tm1Koss>,Pbx2<tm1Mlc>/Pbx2<+>,Nkx2-5<tm2(cre)Rph>/Nkx2-5<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NK2 homeobox 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97350
• pre B cell leukemia homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341793
• pre B cell leukemia homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97495

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pbx1<tm1Koss>/Pbx1<tm1Koss>,Pbx2<tm1Mlc>/Pbx2<+>,Nkx2-5<tm2(cre)Rph>/Nkx2-5<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nkx2-5<+>|Nkx2-5<tm2(cre)Rph>|Pbx2<tm1Mlc>|Pbx1<tm1Koss>|Pbx2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S/Sv * 129S1/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal spleen morphology
  http://purl.obolibrary.org/obo/MP_0000689

文献

http://purl.org/net/cito/citesAsAuthority

• Matthew. Koss, et.al., Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module., Developmental cell, 2012, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/22560297