spleen hypoplasia_Pbx1<tm1Koss>/Pbx1<tm1Koss>,Nkx2-5<tm2(cre)Rph>/Nkx2-5<+>

http://metadb.riken.jp/0000694I129P2OlaHsd129S1SvPbx1tm1KossPbx1tm1KossNkx25tm2creRphNkx25Nkx25Nkx25tm2creRphPbx1tm1Koss

spleen hypoplasia_Pbx1<tm1Koss>/Pbx1<tm1Koss>,Nkx2-5<tm2(cre)Rph>/Nkx2-5<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pre B cell leukemia homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97495
• NK2 homeobox 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97350

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pbx1<tm1Koss>/Pbx1<tm1Koss>,Nkx2-5<tm2(cre)Rph>/Nkx2-5<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nkx2-5<+>|Nkx2-5<tm2(cre)Rph>|Pbx1<tm1Koss>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• spleen hypoplasia
  http://purl.obolibrary.org/obo/MP_0000694

文献

http://purl.org/net/cito/citesAsAuthority

• Matthew. Koss, et.al., Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module., Developmental cell, 2012, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/22560297