decreased thymocyte number_Cops5<tm1Rpar>/Cops5<tm1Rpar>,Tg(Lck-cre)548Jxm/0,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0000715I129C57BL6CBASJLCops5tm1RparCops5tm1RparTgLckcre548Jxm0Trp53tm1TyjTrp53tm1TyjTrp53tm1TyjTgLckcre548JxmCops5tm1Rpar

decreased thymocyte number_Cops5<tm1Rpar>/Cops5<tm1Rpar>,Tg(Lck-cre)548Jxm/0,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• COP9 signalosome subunit 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1349415
• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cops5<tm1Rpar>/Cops5<tm1Rpar>,Tg(Lck-cre)548Jxm/0,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Tg(Lck-cre)548Jxm|Cops5<tm1Rpar>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased thymocyte number
  http://purl.obolibrary.org/obo/MP_0000715

文献

http://purl.org/net/cito/citesAsAuthority

• Martina. Panattoni, et.al., Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development., The Journal of experimental medicine, 2008, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/18268034