decreased thymocyte number_H2<b>/H2<b>,Ptcra<tm1Vbo>/Ptcra<tm1Vbo>,Tcra<tm1Mom>/Tcra/Tcrd<tm1.1(Tcra)Rsky>,Tg(Tcrb)93Vbo/?

http://metadb.riken.jp/0000715I129P2OlaHsdC57BL6JDBA2JH2bH2bPtcratm1VboPtcratm1VboTcratm1MomTcraTcrdtm11TcraRskyTgTcrb93VboH2bTcraTcrdtm11TcraRskyTgTcrb93VboPtcratm1VboTcratm1Mom

decreased thymocyte number_H2<b>/H2<b>,Ptcra<tm1Vbo>/Ptcra<tm1Vbo>,Tcra<tm1Mom>/Tcra/Tcrd<tm1.1(Tcra)Rsky>,Tg(Tcrb)93Vbo/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• T cell receptor alpha chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:98553
• histocompatibility-2, MHC
  http://metadb.riken.jp/db/mgi_rdf/MGI:95894
• transgene insertion 93, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3056728
• pre T cell antigen receptor alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:104857

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2<b>/H2<b>,Ptcra<tm1Vbo>/Ptcra<tm1Vbo>,Tcra<tm1Mom>/Tcra/Tcrd<tm1.1(Tcra)Rsky>,Tg(Tcrb)93Vbo/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• H2<b>|Tcra/Tcrd<tm1.1(Tcra)Rsky>|Tg(Tcrb)93Vbo|Ptcra<tm1Vbo>|Tcra<tm1Mom>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased thymocyte number
  http://purl.obolibrary.org/obo/MP_0000715

文献

http://purl.org/net/cito/citesAsAuthority

• Andrew L. Croxford, et.al., MHC-restricted T cell receptor signaling is required for alpha beta TCR replacement of the pre T cell receptor., European journal of immunology, 2008, 38
  http://rdf.ncbi.nlm.nih.gov/pubmed/18203137