decreased thymocyte number_Cd8b1<tm1Litt>/Cd8b1<+>,Tg(Cd8b1)46Erob/0

http://metadb.riken.jp/0000715I129S4SvJaeC57BL6CBACd8b1tm1LittCd8b1TgCd8b146Erob0TgCd8b146ErobCd8b1Cd8b1tm1Litt

decreased thymocyte number_Cd8b1<tm1Litt>/Cd8b1<+>,Tg(Cd8b1)46Erob/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD8 antigen, beta chain 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88347
• transgene insertion 46, Ellen Robey
  http://metadb.riken.jp/db/mgi_rdf/MGI:3663517

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd8b1<tm1Litt>/Cd8b1<+>,Tg(Cd8b1)46Erob/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd8b1)46Erob|Cd8b1<+>|Cd8b1<tm1Litt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased thymocyte number
  http://purl.obolibrary.org/obo/MP_0000715

文献

http://purl.org/net/cito/citesAsAuthority

• H Y. Irie, et.al., The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development., Journal of immunology (Baltimore, Md. : 1950), 1998, 161
  http://rdf.ncbi.nlm.nih.gov/pubmed/9647223