muscle weakness_Gt(ROSA)26Sor<tm1(Kcnj11*V59M)Fmas>/Gt(ROSA)26Sor<+>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0000747I129S4SvJaeC57BL6SJLGtROSA26Sortm1Kcnj11V59MFmasGtROSA26SorTgNescre1Kln0GtROSA26SorTgNescre1KlnGtROSA26Sortm1Kcnj11V59MFmas

muscle weakness_Gt(ROSA)26Sor<tm1(Kcnj11*V59M)Fmas>/Gt(ROSA)26Sor<+>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Kcnj11*V59M)Fmas>/Gt(ROSA)26Sor<+>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Tg(Nes-cre)1Kln|Gt(ROSA)26Sor<tm1(Kcnj11*V59M)Fmas>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• muscle weakness
  http://purl.obolibrary.org/obo/MP_0000747

文献

http://purl.org/net/cito/citesAsAuthority

• Rebecca H. Clark, et.al., Muscle dysfunction caused by a KATP channel mutation in neonatal diabetes is neuronal in origin., Science (New York, N.Y.), 2010, 329
  http://rdf.ncbi.nlm.nih.gov/pubmed/20595581