abnormal skeletal muscle morphology_Cfl2<tm1Itl>/Cfl2<tm1Itl>,Tg(ACTA1-cre)79Jme/0

http://metadb.riken.jp/0000759IC57BL6JC57BL6NTacSJLCfl2tm1ItlCfl2tm1ItlTgACTA1cre79Jme0TgACTA1cre79JmeCfl2tm1Itl

abnormal skeletal muscle morphology_Cfl2<tm1Itl>/Cfl2<tm1Itl>,Tg(ACTA1-cre)79Jme/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cofilin 2, muscle
  http://metadb.riken.jp/db/mgi_rdf/MGI:101763
• transgene insertion 79, Judith Melki
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447634

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cfl2<tm1Itl>/Cfl2<tm1Itl>,Tg(ACTA1-cre)79Jme/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(ACTA1-cre)79Jme|Cfl2<tm1Itl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * C57BL/6NTac * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal skeletal muscle morphology
  http://purl.obolibrary.org/obo/MP_0000759

文献

http://purl.org/net/cito/citesAsAuthority

• Pankaj B. Agrawal, et.al., Normal myofibrillar development followed by progressive sarcomeric disruption with actin accumulations in a mouse Cfl2 knockout demonstrates requirement of cofilin-2 for muscle maintenance., Human molecular genetics, 2012, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/22343409