abnormal cerebellar foliation_En1<tm2(cre)Wrst>/?,Gli3<tm1Alj>/Gli3<tm1Alj>,Smo<tm2Amc>/Smo<tm2Amc>

http://metadb.riken.jp/0000857I129S1Sv129S6SvEvTac129X1SvJC57BL6En1tm2creWrstGli3tm1AljGli3tm1AljSmotm2AmcSmotm2AmcSmotm2AmcGli3tm1AljEn1tm2creWrst

abnormal cerebellar foliation_En1<tm2(cre)Wrst>/?,Gli3<tm1Alj>/Gli3<tm1Alj>,Smo<tm2Amc>/Smo<tm2Amc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• smoothened, frizzled class receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:108075
• engrailed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95389
• GLI-Kruppel family member GLI3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95729

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• En1<tm2(cre)Wrst>/?,Gli3<tm1Alj>/Gli3<tm1Alj>,Smo<tm2Amc>/Smo<tm2Amc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smo<tm2Amc>|Gli3<tm1Alj>|En1<tm2(cre)Wrst>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cerebellar foliation
  http://purl.obolibrary.org/obo/MP_0000857

文献

http://purl.org/net/cito/citesAsAuthority

• Sandra. Blaess, et.al., Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling., Development (Cambridge, England), 2008, 135
  http://rdf.ncbi.nlm.nih.gov/pubmed/18480159