absent barrels in primary somatosensory cortex_Emx1<tm1(cre)Ito>/Emx1<+>,Grin1<tm1Stl>/Grin1<tm2Stl>

http://metadb.riken.jp/0000862I129P2OlaHsd129S2SvPas129S4SvJaeC57BL6Emx1tm1creItoEmx1Grin1tm1StlGrin1tm2StlGrin1tm1StlEmx1Grin1tm2StlEmx1tm1creIto

absent barrels in primary somatosensory cortex_Emx1<tm1(cre)Ito>/Emx1<+>,Grin1<tm1Stl>/Grin1<tm2Stl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutamate receptor, ionotropic, NMDA1 (zeta 1)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95819
• empty spiracles homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95387

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Emx1<tm1(cre)Ito>/Emx1<+>,Grin1<tm1Stl>/Grin1<tm2Stl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grin1<tm1Stl>|Emx1<+>|Grin1<tm2Stl>|Emx1<tm1(cre)Ito>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absent barrels in primary somatosensory cortex
  http://purl.obolibrary.org/obo/MP_0000862

文献

http://purl.org/net/cito/citesAsAuthority

• T. Iwasato, et.al., Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex., Nature, 2000, 406
  http://rdf.ncbi.nlm.nih.gov/pubmed/10963597
• Akash. Datwani, et.al., NMDA receptor-dependent pattern transfer from afferents to postsynaptic cells and dendritic differentiation in the barrel cortex., Molecular and cellular neurosciences, 2002, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/12498788