abnormal cerebellum vermis morphology_Trp53<tm1Brd>/Trp53<tm1Brd>,Xrcc4<tm2.1Fwa>/Xrcc4<tm2Fwa>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0000864I129S6SvEvTac129S7SvEvBrdC57BL6SJLTrp53tm1BrdTrp53tm1BrdXrcc4tm21FwaXrcc4tm2FwaTgNescre1Kln0Xrcc4tm2FwaXrcc4tm21FwaTrp53tm1BrdTgNescre1Kln

abnormal cerebellum vermis morphology_Trp53<tm1Brd>/Trp53<tm1Brd>,Xrcc4<tm2.1Fwa>/Xrcc4<tm2Fwa>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• X-ray repair complementing defective repair in Chinese hamster cells 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1333799

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brd>/Trp53<tm1Brd>,Xrcc4<tm2.1Fwa>/Xrcc4<tm2Fwa>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Xrcc4<tm2Fwa>|Xrcc4<tm2.1Fwa>|Trp53<tm1Brd>|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cerebellum vermis morphology
  http://purl.obolibrary.org/obo/MP_0000864

文献

http://purl.org/net/cito/citesAsAuthority

• Catherine T. Yan, et.al., XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/16670198