abnormal cerebellum external granule cell layer morphology_Itgb1<tm1Mll>/Itgb1<tm1Mll>,Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Tg(Nes-cre/Esr1*)1Kuan/0

http://metadb.riken.jp/0000872I129S1Sv129X1SvJC57BL6FVBItgb1tm1MllItgb1tm1MllGtROSA26Sortm4ACTBtdTomatoEGFPLuoGtROSA26SorTgNescreEsr11Kuan0Itgb1tm1MllGtROSA26Sortm4ACTBtdTomatoEGFPLuoTgNescreEsr11KuanGtROSA26Sor

abnormal cerebellum external granule cell layer morphology_Itgb1<tm1Mll>/Itgb1<tm1Mll>,Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Tg(Nes-cre/Esr1*)1Kuan/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• integrin beta 1 (fibronectin receptor beta)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96610
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Chia-Yi Kuan
  http://metadb.riken.jp/db/mgi_rdf/MGI:4420447

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itgb1<tm1Mll>/Itgb1<tm1Mll>,Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Tg(Nes-cre/Esr1*)1Kuan/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itgb1<tm1Mll>|Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>|Tg(Nes-cre/Esr1*)1Kuan|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cerebellum external granule cell layer morphology
  http://purl.obolibrary.org/obo/MP_0000872

文献

http://purl.org/net/cito/citesAsAuthority

• Shang. Ma, et.al., Ric-8a, a guanine nucleotide exchange factor for heterotrimeric G proteins, regulates bergmann glia-basement membrane adhesion during cerebellar foliation., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/23100420