Purkinje cell degeneration_Dnajc3<tm8663Wcl>/Dnajc3<tm8663Wcl>,Sil1<Gt(RST462)Byg>/Sil1<Gt(RST462)Byg>

http://metadb.riken.jp/0000876I129P2OlaHsdC57BL6C57BL6JDnajc3tm8663WclDnajc3tm8663WclSil1GtRST462BygSil1GtRST462BygSil1GtRST462BygDnajc3tm8663Wcl

Purkinje cell degeneration_Dnajc3<tm8663Wcl>/Dnajc3<tm8663Wcl>,Sil1<Gt(RST462)Byg>/Sil1<Gt(RST462)Byg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• DnaJ heat shock protein family (Hsp40) member C3
  http://metadb.riken.jp/db/mgi_rdf/MGI:107373
• endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1932040

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dnajc3<tm8663Wcl>/Dnajc3<tm8663Wcl>,Sil1<Gt(RST462)Byg>/Sil1<Gt(RST462)Byg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sil1<Gt(RST462)Byg>|Dnajc3<tm8663Wcl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• Purkinje cell degeneration
  http://purl.obolibrary.org/obo/MP_0000876

文献

http://purl.org/net/cito/citesAsAuthority

• Lihong. Zhao, et.al., Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjögren syndrome., Human molecular genetics, 2010, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/19801575