Purkinje cell degeneration_Cacna1a<tm1Kano>/Cacna1a<tm1Kano>,Grid2<tm1(cre)Mwa>/Grid2<+>

http://metadb.riken.jp/0000876IC57BL6NCacna1atm1KanoCacna1atm1KanoGrid2tm1creMwaGrid2Grid2tm1creMwaGrid2Cacna1atm1Kano

Purkinje cell degeneration_Cacna1a<tm1Kano>/Cacna1a<tm1Kano>,Grid2<tm1(cre)Mwa>/Grid2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:109482
• glutamate receptor, ionotropic, delta 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95813

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cacna1a<tm1Kano>/Cacna1a<tm1Kano>,Grid2<tm1(cre)Mwa>/Grid2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grid2<tm1(cre)Mwa>|Grid2<+>|Cacna1a<tm1Kano>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• Purkinje cell degeneration
  http://purl.obolibrary.org/obo/MP_0000876

文献

http://purl.org/net/cito/citesAsAuthority

• Taisuke. Miyazaki, et.al., Cav2.1 in cerebellar Purkinje cells regulates competitive excitatory synaptic wiring, cell survival, and cerebellar biochemical compartmentalization., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22279216