abnormal Purkinje cell morphology_Calb1<tm1Mpin>/Calb1<tm1Mpin>,Pvalb<tm1Swal>/Pvalb<tm1Swal>

http://metadb.riken.jp/0000877I129P2OlaHsd129S1Sv129X1SvJC57BL6JCalb1tm1MpinCalb1tm1MpinPvalbtm1SwalPvalbtm1SwalPvalbtm1SwalCalb1tm1Mpin

abnormal Purkinje cell morphology_Calb1<tm1Mpin>/Calb1<tm1Mpin>,Pvalb<tm1Swal>/Pvalb<tm1Swal>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• calbindin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88248
• parvalbumin
  http://metadb.riken.jp/db/mgi_rdf/MGI:97821

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Calb1<tm1Mpin>/Calb1<tm1Mpin>,Pvalb<tm1Swal>/Pvalb<tm1Swal>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pvalb<tm1Swal>|Calb1<tm1Mpin>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal Purkinje cell morphology
  http://purl.obolibrary.org/obo/MP_0000877

文献

http://purl.org/net/cito/citesAsAuthority

• G. Chen, et.al., Deficiency in parvalbumin, but not in calbindin D-28k upregulates mitochondrial volume and decreases smooth endoplasmic reticulum surface selectively in a peripheral, subplasmalemmal region in the soma of Purkinje cells., Neuroscience, 2006, 142
  http://rdf.ncbi.nlm.nih.gov/pubmed/16860487