decreased Purkinje cell number_Cacna1g<tm1Hssh>/Cacna1g<tm1Hssh>,Gabra1<tm1.1Geh>/Gabra1<tm1.1Geh>

http://metadb.riken.jp/0000880I129S1Sv129S4SvJae129X1SvJC57BL6JCacna1gtm1HsshCacna1gtm1HsshGabra1tm11GehGabra1tm11GehCacna1gtm1HsshGabra1tm11Geh

decreased Purkinje cell number_Cacna1g<tm1Hssh>/Cacna1g<tm1Hssh>,Gabra1<tm1.1Geh>/Gabra1<tm1.1Geh>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• calcium channel, voltage-dependent, T type, alpha 1G subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1201678
• gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95613

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cacna1g<tm1Hssh>/Cacna1g<tm1Hssh>,Gabra1<tm1.1Geh>/Gabra1<tm1.1Geh>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cacna1g<tm1Hssh>|Gabra1<tm1.1Geh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Purkinje cell number
  http://purl.obolibrary.org/obo/MP_0000880

文献

http://purl.org/net/cito/citesAsAuthority

• Ki-Young. Chang, et.al., Lack of CaV3.1 channels causes severe motor coordination defects and an age-dependent cerebellar atrophy in a genetic model of essential tremor., Biochemical and biophysical research communications, 2011, 410
  http://rdf.ncbi.nlm.nih.gov/pubmed/21621520