abnormal cerebellar granule layer morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>

http://metadb.riken.jp/0000886I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln

abnormal cerebellar granule layer morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• triple functional domain (PTPRF interacting)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927230
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trio<tm1Mzhu>|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cerebellar granule layer morphology
  http://purl.obolibrary.org/obo/MP_0000886

文献

http://purl.org/net/cito/citesAsAuthority

• Ya-Jing. Peng, et.al., Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20516067