abnormal midbrain morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>

http://metadb.riken.jp/0000897I129S4SvJaeC57BL6Ptentm1HwuPtentm1HwuSlc6a3tm11creBkmnSlc6a3Slc6a3tm11creBkmnSlc6a3Ptentm1Hwu

abnormal midbrain morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:94862
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc6a3<tm1.1(cre)Bkmn>|Slc6a3<+>|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal midbrain morphology
  http://purl.obolibrary.org/obo/MP_0000897

文献

http://purl.org/net/cito/citesAsAuthority

• Oscar. Diaz-Ruiz, et.al., Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons., PloS one, 2009, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/19750226