exencephaly_Med12<tm1.1Hsch>/Med12<+>,Tg(CMV-cre)1Cgn/0

http://metadb.riken.jp/0000914I129S6SvEvTacC57BL6Med12tm11HschMed12TgCMVcre1Cgn0TgCMVcre1CgnMed12Med12tm11Hsch

exencephaly_Med12<tm1.1Hsch>/Med12<+>,Tg(CMV-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mediator complex subunit 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926212
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176179

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Med12<tm1.1Hsch>/Med12<+>,Tg(CMV-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CMV-cre)1Cgn|Med12<+>|Med12<tm1.1Hsch>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• exencephaly
  http://purl.obolibrary.org/obo/MP_0000914

文献

http://purl.org/net/cito/citesAsAuthority

• Pedro P. Rocha, et.al., Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida, and craniorachischisis., Birth defects research. Part A, Clinical and molecular teratology, 2010, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/20589884