demyelination_Rag2<tm1.1Cgn>/Rag2<tm1.1Cgn>,Tg(HLA-DR2)#Lfug/0,Tg(TCROb.1A12)#Lfug/0

http://metadb.riken.jp/0000921IC57BL6DBA2Rag2tm11CgnRag2tm11CgnTgHLADR2Lfug0TgTCROb1A12Lfug0TgTCROb1A12LfugRag2tm11CgnTgHLADR2Lfug

demyelination_Rag2<tm1.1Cgn>/Rag2<tm1.1Cgn>,Tg(HLA-DR2)#Lfug/0,Tg(TCROb.1A12)#Lfug/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Lars Fugger
  http://metadb.riken.jp/db/mgi_rdf/MGI:5429699
• transgene insertion, Lars Fugger
  http://metadb.riken.jp/db/mgi_rdf/MGI:5429697
• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rag2<tm1.1Cgn>/Rag2<tm1.1Cgn>,Tg(HLA-DR2)#Lfug/0,Tg(TCROb.1A12)#Lfug/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TCROb.1A12)#Lfug|Rag2<tm1.1Cgn>|Tg(HLA-DR2)#Lfug

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• demyelination
  http://purl.obolibrary.org/obo/MP_0000921

文献

http://purl.org/net/cito/citesAsAuthority

• L S. Madsen, et.al., A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor., Nature genetics, 1999, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/10610182