motor neuron degeneration_Gt(ROSA)26Sor<tm1(GRN)Pvd>/Gt(ROSA)26Sor<tm1(GRN)Pvd>,Tg(Pgk1-cre)1Lni/0,Tg(SOD1*G93A)1Gur/0

http://metadb.riken.jp/0000938B6JCgTgPgk1cre1LniGtROSA26Sortm1GRNPvdTgSOD1G93A1GurGtROSA26Sortm1GRNPvdGtROSA26Sortm1GRNPvdTgPgk1cre1Lni0TgSOD1G93A1Gur0TgSOD1G93A1GurTgPgk1cre1LniGtROSA26Sortm1GRNPvd

motor neuron degeneration_Gt(ROSA)26Sor<tm1(GRN)Pvd>/Gt(ROSA)26Sor<tm1(GRN)Pvd>,Tg(Pgk1-cre)1Lni/0,Tg(SOD1*G93A)1Gur/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Mark E Gurney
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388308
• transgene insertion 1, Peter Lonai
  http://metadb.riken.jp/db/mgi_rdf/MGI:2178049

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(GRN)Pvd>/Gt(ROSA)26Sor<tm1(GRN)Pvd>,Tg(Pgk1-cre)1Lni/0,Tg(SOD1*G93A)1Gur/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(SOD1*G93A)1Gur|Tg(Pgk1-cre)1Lni|Gt(ROSA)26Sor<tm1(GRN)Pvd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6J.Cg-Tg(Pgk1-cre)1Lni Gt(ROSA)26Sor<tm1(GRN)Pvd> Tg(SOD1*G93A)1Gur

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• motor neuron degeneration
  http://purl.obolibrary.org/obo/MP_0000938

文献

http://purl.org/net/cito/citesAsAuthority

• Sarah. Herdewyn, et.al., Progranulin does not affect motor neuron degeneration in mutant SOD1 mice and rats., Neurobiology of aging, 2013, 34
  http://rdf.ncbi.nlm.nih.gov/pubmed/23608112