motor neuron degeneration_Spg11<Gt(EUCE0085f05)Hmgu>/Spg11<Gt(EUCE0085f05)Hmgu>

http://metadb.riken.jp/0000938I129P2OlaHsdC57BL6Spg11GtEUCE0085f05HmguSpg11GtEUCE0085f05HmguSpg11GtEUCE0085f05Hmgu

motor neuron degeneration_Spg11<Gt(EUCE0085f05)Hmgu>/Spg11<Gt(EUCE0085f05)Hmgu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SPG11, spatacsin vesicle trafficking associated
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444989

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Spg11<Gt(EUCE0085f05)Hmgu>/Spg11<Gt(EUCE0085f05)Hmgu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Spg11<Gt(EUCE0085f05)Hmgu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• motor neuron degeneration
  http://purl.obolibrary.org/obo/MP_0000938

文献

http://purl.org/net/cito/citesAsAuthority

• Rita-Eva. Varga, et.al., In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11., PLoS genetics, 2015, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/26284655