motor neuron degeneration_Bbc3<tm1Ast>/Bbc3<tm1Ast>,Tg(SOD1*G93A)1Gur/0

http://metadb.riken.jp/0000938IC57BL6NZBSJLBbc3tm1AstBbc3tm1AstTgSOD1G93A1Gur0Bbc3tm1AstTgSOD1G93A1Gur

motor neuron degeneration_Bbc3<tm1Ast>/Bbc3<tm1Ast>,Tg(SOD1*G93A)1Gur/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Mark E Gurney
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388308
• BCL2 binding component 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2181667

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bbc3<tm1Ast>/Bbc3<tm1Ast>,Tg(SOD1*G93A)1Gur/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bbc3<tm1Ast>|Tg(SOD1*G93A)1Gur

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * NZB * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• motor neuron degeneration
  http://purl.obolibrary.org/obo/MP_0000938

文献

http://purl.org/net/cito/citesAsAuthority

• Dairín. Kieran, et.al., Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/18077368