motor neuron degeneration_Tg(SOD1*G93A)1Gur/0

http://metadb.riken.jp/0000938IC57BL6SJLTgSOD1G93A1Gur0TgSOD1G93A1Gur

motor neuron degeneration_Tg(SOD1*G93A)1Gur/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Mark E Gurney
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388308

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(SOD1*G93A)1Gur/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(SOD1*G93A)1Gur

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• motor neuron degeneration
  http://purl.obolibrary.org/obo/MP_0000938

文献

http://purl.org/net/cito/citesAsAuthority

• Dairín. Kieran, et.al., Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/18077368
• P H. Tu, et.al., Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions., Proceedings of the National Academy of Sciences of the United States of America, 1996, 93
  http://rdf.ncbi.nlm.nih.gov/pubmed/8610185