decreased motor neuron number_Gemin2<tm1Msd>/Gemin2<+>,Smn1<tm1Msd>/Smn1<+>

http://metadb.riken.jp/0000939I129P2OlaHsdC57BL6MF1Gemin2tm1MsdGemin2Smn1tm1MsdSmn1Gemin2tm1MsdGemin2Smn1Smn1tm1Msd

decreased motor neuron number_Gemin2<tm1Msd>/Gemin2<+>,Smn1<tm1Msd>/Smn1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• survival motor neuron 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109257
• gem nuclear organelle associated protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913853

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gemin2<tm1Msd>/Gemin2<+>,Smn1<tm1Msd>/Smn1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gemin2<tm1Msd>|Gemin2<+>|Smn1<+>|Smn1<tm1Msd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * MF1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased motor neuron number
  http://purl.obolibrary.org/obo/MP_0000939

文献

http://purl.org/net/cito/citesAsAuthority

• Sibylle. Jablonka, et.al., Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/12091709