convulsive seizures_Scn1a<tm2.1Kzy>/Scn1a<tm2.1Kzy>,Tg(Pvalb-cre)1Tama/0

http://metadb.riken.jp/0000947I129P2OlaHsdC57BL6DBAScn1atm21KzyScn1atm21KzyTgPvalbcre1Tama0Scn1atm21KzyTgPvalbcre1Tama

convulsive seizures_Scn1a<tm2.1Kzy>/Scn1a<tm2.1Kzy>,Tg(Pvalb-cre)1Tama/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sodium channel, voltage-gated, type I, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:98246
• transgene insertion 1, Nobuaki Tamamaki
  http://metadb.riken.jp/db/mgi_rdf/MGI:3837559

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Scn1a<tm2.1Kzy>/Scn1a<tm2.1Kzy>,Tg(Pvalb-cre)1Tama/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Scn1a<tm2.1Kzy>|Tg(Pvalb-cre)1Tama

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• convulsive seizures
  http://purl.obolibrary.org/obo/MP_0000947

文献

http://purl.org/net/cito/citesAsAuthority

• Ikuo. Ogiwara, et.al., Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome., Human molecular genetics, 2013, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/23922229