abnormal enteric ganglia morphology_Gfra1<tm1Jmi>/Gfra1<tm2Jmi>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0001045I129SvC57BL6CBASJLGfra1tm1JmiGfra1tm2JmiTgCAGcreEsr15Amc0Gfra1tm1JmiGfra1tm2JmiTgCAGcreEsr15Amc

abnormal enteric ganglia morphology_Gfra1<tm1Jmi>/Gfra1<tm2Jmi>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glial cell line derived neurotrophic factor family receptor alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100842
• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gfra1<tm1Jmi>/Gfra1<tm2Jmi>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gfra1<tm1Jmi>|Gfra1<tm2Jmi>|Tg(CAG-cre/Esr1*)5Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal enteric ganglia morphology
  http://purl.obolibrary.org/obo/MP_0001045

文献

http://purl.org/net/cito/citesAsAuthority

• Toshihiro. Uesaka, et.al., Conditional ablation of GFRalpha1 in postmigratory enteric neurons triggers unconventional neuronal death in the colon and causes a Hirschsprung's disease phenotype., Development (Cambridge, England), 2007, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/17507417