abnormal neuromuscular synapse morphology_Chat<tm2(cre)Lowl>/Chat<+>,Mapt<tm2(FUS)Neas>/Mapt<+>

http://metadb.riken.jp/0001053B6129Mapttm2FUSNeasChattm2creLowlChattm2creLowlChatMapttm2FUSNeasMaptMapttm2FUSNeasChattm2creLowlMaptChat

abnormal neuromuscular synapse morphology_Chat<tm2(cre)Lowl>/Chat<+>,Mapt<tm2(FUS)Neas>/Mapt<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• choline acetyltransferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88392
• microtubule-associated protein tau
  http://metadb.riken.jp/db/mgi_rdf/MGI:97180

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chat<tm2(cre)Lowl>/Chat<+>,Mapt<tm2(FUS)Neas>/Mapt<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapt<tm2(FUS)Neas>|Chat<tm2(cre)Lowl>|Mapt<+>|Chat<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129-Mapt<tm2(FUS)Neas> Chat<tm2(cre)Lowl>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal neuromuscular synapse morphology
  http://purl.obolibrary.org/obo/MP_0001053

文献

http://purl.org/net/cito/citesAsAuthority

• Aarti. Sharma, et.al., ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function., Nature communications, 2016, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/26842965