failure of neuromuscular synapse presynaptic differentiation_Agrn<tm4Jrs>/Agrn<tm4Jrs>,Chrna1<tm1Klee>/Chrna1<tm1Klee>,Chrna7<tm1Bay>/Chrna7<tm1Bay>

http://metadb.riken.jp/0001054I129S4SvJae129S7SvEvBrdC57BL6Agrntm4JrsAgrntm4JrsChrna1tm1KleeChrna1tm1KleeChrna7tm1BayChrna7tm1BayChrna7tm1BayChrna1tm1KleeAgrntm4Jrs

failure of neuromuscular synapse presynaptic differentiation_Agrn<tm4Jrs>/Agrn<tm4Jrs>,Chrna1<tm1Klee>/Chrna1<tm1Klee>,Chrna7<tm1Bay>/Chrna7<tm1Bay>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
  http://metadb.riken.jp/db/mgi_rdf/MGI:87885
• agrin
  http://metadb.riken.jp/db/mgi_rdf/MGI:87961
• cholinergic receptor, nicotinic, alpha polypeptide 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:99779

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Agrn<tm4Jrs>/Agrn<tm4Jrs>,Chrna1<tm1Klee>/Chrna1<tm1Klee>,Chrna7<tm1Bay>/Chrna7<tm1Bay>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chrna7<tm1Bay>|Chrna1<tm1Klee>|Agrn<tm4Jrs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• failure of neuromuscular synapse presynaptic differentiation
  http://purl.obolibrary.org/obo/MP_0001054

文献

http://purl.org/net/cito/citesAsAuthority

• Mahru C. An, et.al., Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20498043