decreased Schwann cell number_Nrg1<tm1Cbm>/Nrg1<tm3Cbm>,Isl1<tm1(cre)Tmj>/Isl1<+>

http://metadb.riken.jp/0001107I129P2OlaHsd129X1SvJNrg1tm1CbmNrg1tm3CbmIsl1tm1creTmjIsl1Isl1tm1creTmjIsl1Nrg1tm3CbmNrg1tm1Cbm

decreased Schwann cell number_Nrg1<tm1Cbm>/Nrg1<tm3Cbm>,Isl1<tm1(cre)Tmj>/Isl1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neuregulin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96083
• ISL1 transcription factor, LIM/homeodomain
  http://metadb.riken.jp/db/mgi_rdf/MGI:101791

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nrg1<tm1Cbm>/Nrg1<tm3Cbm>,Isl1<tm1(cre)Tmj>/Isl1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Isl1<tm1(cre)Tmj>|Isl1<+>|Nrg1<tm3Cbm>|Nrg1<tm1Cbm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Schwann cell number
  http://purl.obolibrary.org/obo/MP_0001107

文献

http://purl.org/net/cito/citesAsAuthority

• Simon. Hippenmeyer, et.al., A role for neuregulin1 signaling in muscle spindle differentiation., Neuron, 2002, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/12495620