decreased Schwann cell number_Mtor<tm1Koz>/Mtor<tm1Koz>,Cnp<tm1(cre)Kan>/Cnp<+>

http://metadb.riken.jp/0001107I129S4SvJaeC57BL6Mtortm1KozMtortm1KozCnptm1creKanCnpCnptm1creKanCnpMtortm1Koz

decreased Schwann cell number_Mtor<tm1Koz>/Mtor<tm1Koz>,Cnp<tm1(cre)Kan>/Cnp<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• 2',3'-cyclic nucleotide 3' phosphodiesterase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88437
• mechanistic target of rapamycin (serine/threonine kinase)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928394

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mtor<tm1Koz>/Mtor<tm1Koz>,Cnp<tm1(cre)Kan>/Cnp<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cnp<tm1(cre)Kan>|Cnp<+>|Mtor<tm1Koz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Schwann cell number
  http://purl.obolibrary.org/obo/MP_0001107

文献

http://purl.org/net/cito/citesAsAuthority

• Diane L. Sherman, et.al., Arrest of myelination and reduced axon growth when Schwann cells lack mTOR., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22302821