abnormal prostate gland anterior lobe morphology_Klf6<tm1Fjs>/Klf6<tm1Fjs>,Nkx3-1<tm3(cre)Mms>/Nkx3-1<+>

http://metadb.riken.jp/0001163I129SvC57BL6Klf6tm1FjsKlf6tm1FjsNkx31tm3creMmsNkx31Klf6tm1FjsNkx31Nkx31tm3creMms

abnormal prostate gland anterior lobe morphology_Klf6<tm1Fjs>/Klf6<tm1Fjs>,Nkx3-1<tm3(cre)Mms>/Nkx3-1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NK-3 transcription factor, locus 1 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:97352
• Kruppel-like factor 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346318

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Klf6<tm1Fjs>/Klf6<tm1Fjs>,Nkx3-1<tm3(cre)Mms>/Nkx3-1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Klf6<tm1Fjs>|Nkx3-1<+>|Nkx3-1<tm3(cre)Mms>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal prostate gland anterior lobe morphology
  http://purl.obolibrary.org/obo/MP_0001163

文献

http://purl.org/net/cito/citesAsAuthority

• Ching Ching. Leow, et.al., Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19494112