prostate gland epithelial hyperplasia_Pten<tm1Mro>/Pten<tm1Mro>,Tg(KLK3-cre)D4Trp/0

http://metadb.riken.jp/0001167I129P2OlaHsdFVBPtentm1MroPtentm1MroTgKLK3creD4Trp0TgKLK3creD4TrpPtentm1Mro

prostate gland epithelial hyperplasia_Pten<tm1Mro>/Pten<tm1Mro>,Tg(KLK3-cre)D4Trp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion D4, Jan Trapman
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761847

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Mro>/Pten<tm1Mro>,Tg(KLK3-cre)D4Trp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KLK3-cre)D4Trp|Pten<tm1Mro>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• prostate gland epithelial hyperplasia
  http://purl.obolibrary.org/obo/MP_0001167

文献

http://purl.org/net/cito/citesAsAuthority

• Xiaoqian. Ma, et.al., Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis., Cancer research, 2005, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/15994948