abnormal lung morphology_Nedd4l<tm1.1Dro>/Nedd4l<tm1.1Dro>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0

http://metadb.riken.jp/0001175I129P2OlaHsdC57BL6FVBNSJLNedd4ltm11DroNedd4ltm11DroTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawTgSFTPCrtTA5JawNedd4ltm11Dro

abnormal lung morphology_Nedd4l<tm1.1Dro>/Nedd4l<tm1.1Dro>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neural precursor cell expressed, developmentally down-regulated gene 4-like
  http://metadb.riken.jp/db/mgi_rdf/MGI:1933754
• transgene insertion 5, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679530
• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:3028584

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nedd4l<tm1.1Dro>/Nedd4l<tm1.1Dro>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-cre)1Jaw|Tg(SFTPC-rtTA)5Jaw|Nedd4l<tm1.1Dro>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lung morphology
  http://purl.obolibrary.org/obo/MP_0001175

文献

http://purl.org/net/cito/citesAsAuthority

• Toshihiro. Kimura, et.al., Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21300902