pulmonary hypoplasia_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?

http://metadb.riken.jp/0001178I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw

pulmonary hypoplasia_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679530
• laminin, alpha 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:105382
• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:3028584

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lama5<tm2Jhm>|Lama5<tm1Jhm>|Tg(SFTPC-rtTA)5Jaw|Tg(tetO-cre)1Jaw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• pulmonary hypoplasia
  http://purl.obolibrary.org/obo/MP_0001178

文献

http://purl.org/net/cito/citesAsAuthority

• Nguyet M. Nguyen, et.al., Epithelial laminin alpha5 is necessary for distal epithelial cell maturation, VEGF production, and alveolization in the developing murine lung., Developmental biology, 2005, 282
  http://rdf.ncbi.nlm.nih.gov/pubmed/15936333