dermatitis_Pdpk1<tm1.1Mlw>/Pdpk1<tm1.1Mlw>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0001194I129X1SvJC57BL6Pdpk1tm11MlwPdpk1tm11MlwTnfrsf4tm2creNikTnfrsf4GtROSA26Sortm1EYFPCosGtROSA26SorTnfrsf4tm2creNikPdpk1tm11MlwTnfrsf4GtROSA26Sortm1EYFPCosGtROSA26Sor

dermatitis_Pdpk1<tm1.1Mlw>/Pdpk1<tm1.1Mlw>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• 3-phosphoinositide dependent protein kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338068
• tumor necrosis factor receptor superfamily, member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:104512
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdpk1<tm1.1Mlw>/Pdpk1<tm1.1Mlw>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tnfrsf4<tm2(cre)Nik>|Pdpk1<tm1.1Mlw>|Tnfrsf4<+>|Gt(ROSA)26Sor<tm1(EYFP)Cos>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• dermatitis
  http://purl.obolibrary.org/obo/MP_0001194

文献

http://purl.org/net/cito/citesAsAuthority

• Minjun. Yu, et.al., Conditional PDK1 Ablation Promotes Epidermal and T-Cell-Mediated Dysfunctions Leading to Inflammatory Skin Disease., The Journal of investigative dermatology, 2015, 135
  http://rdf.ncbi.nlm.nih.gov/pubmed/26099023