wrinkled skin_Col1a1<tm1(tetO-YAP1*)Fcam>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(KRT14-cre)1Amc/0

http://metadb.riken.jp/0001211I129S1Sv129S4SvJae129X1SvJC57BL6CBACol1a1tm1tetOYAP1FcamCol1a1GtROSA26Sortm1rtTAEGFPNagyGtROSA26SorTgKRT14cre1Amc0GtROSA26SorTgKRT14cre1AmcCol1a1tm1tetOYAP1FcamCol1a1GtROSA26Sortm1rtTAEGFPNagy

wrinkled skin_Col1a1<tm1(tetO-YAP1*)Fcam>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(KRT14-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450263
• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm1(tetO-YAP1*)Fcam>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(KRT14-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Tg(KRT14-cre)1Amc|Col1a1<tm1(tetO-YAP1*)Fcam>|Col1a1<+>|Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• wrinkled skin
  http://purl.obolibrary.org/obo/MP_0001211

文献

http://purl.org/net/cito/citesAsAuthority

• Karin. Schlegelmilch, et.al., Yap1 acts downstream of α-catenin to control epidermal proliferation., Cell, 2011, 144
  http://rdf.ncbi.nlm.nih.gov/pubmed/21376238