abnormal dermal layer morphology_Itgb1<tm1Ref>/Itgb1<tm1Ref>,Tg(KRT5-cre)5132Jlj/0

http://metadb.riken.jp/0001243I129S1Sv129X1SvJC57BL6JDBA2JItgb1tm1RefItgb1tm1RefTgKRT5cre5132Jlj0Itgb1tm1RefTgKRT5cre5132Jlj

abnormal dermal layer morphology_Itgb1<tm1Ref>/Itgb1<tm1Ref>,Tg(KRT5-cre)5132Jlj/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5132, Jose Luis Jorcano
  http://metadb.riken.jp/db/mgi_rdf/MGI:3050066
• integrin beta 1 (fibronectin receptor beta)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96610

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itgb1<tm1Ref>/Itgb1<tm1Ref>,Tg(KRT5-cre)5132Jlj/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itgb1<tm1Ref>|Tg(KRT5-cre)5132Jlj

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dermal layer morphology
  http://purl.obolibrary.org/obo/MP_0001243

文献

http://purl.org/net/cito/citesAsAuthority

• C. Brakebusch, et.al., Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes., The EMBO journal, 2000, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/10921880
• Aleksandra. Piwko-Czuchra, et.al., Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion., PloS one, 2009, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/19424505